PRIMARY ROLE

Alto Neuroscience is seeking a dynamic and experienced leader to serve as Vice President, Early-Stage Clinical Development. This role will lead the strategy and execution of early development activities across Alto’s portfolio, spanning toxicology, clinical pharmacology, and translational studies. The VP will provide both high-level scientific direction and hands-on operational oversight, ensuring that each program advances efficiently, compliantly, and with scientific rigor. This position is a critical member of Alto’s leadership team, driving decisions that bridge discovery science and clinical proof-of-concept

DUTIES & RESPONSIBILITIES

• Lead integrated early development strategy and execution for all pipeline assets.

• Design and oversee IND-enabling and early clinical studies.

• Partner cross-functionally to align development, regulatory, and operational plans.

• Manage CRO and vendor relationships for quality, speed, and cost efficiency.

• Build and mentor a growing early development team.

• Represent Alto with regulators, advisors, and external collaborators.

• Ensure compliance with applicable regulations, guidelines, and standards (e.g., GxP, ICH, FDA/EMA expectations) as well as Alto’s internal quality systems and SOPs.

LOCATION

Mountain View, CA or Remote

SALARY RANGE

$285,000 - $305,000

Depending on qualifications and experience level.

Compensation includes a base salary, an annual target bonus, and an equity grant.

QUALIFICATIONS

• Advanced Degree (MD, PhD, or PharmD) with 10+ years in drug development.

• Proven success leading IND-enabling and early-phase studies in biotech or pharma.

• Deep expertise in toxicology, clinical pharmacology, and translational science.

• Strong leadership, communication, and cross-functional collaboration skills.

• Thrives in a dynamic, fast-paced, mission-driven environment.

Why Alto

At Alto Neuroscience, you will play a pivotal role in advancing precision psychiatry and improving how mental health disorders are treated. Join us in building the next generation of personalized neuroscience-based therapeutics.

Alto Neuroscience is an equal-opportunity employer that does not discriminate on the basis of sex, age, race, color, religion, marital status, sexual orientation, gender identity, pregnancy, disability, or any other characteristic protected by law. We offer a welcoming and inclusive environment in service to one another, our products, the diverse consumers we represent, and the communities we call home. We do all of this with kindness, empathy and respect for each other. The above is intended to describe the general content of and requirements for the performance of this job. It should not be construed as an exhaustive statement of duties, responsibilities or physical requirements.

#LI - Remote